10 May – 16 May CEST
Spetses Island, Greece.
The FEBS Advanced Course, Lost in Integration Vol. 2 – probing biomolecules with AI and experiments will take place from 10th to 16th of May 10 2026 on the idyllic island of Spetses in Greece. The course is aimed at PhD candidates and postdoctoral researchers interested in integrative structural biology.
Integrative structural biology is an interdisciplinary field that has seen explosive growth due to technological revolution in biological structure analysis. This field incorporates a wide range of techniques and advanced computational and machine learning approaches. When integrated, these techniques provide insights beyond static molecular structures, revealing dynamic interactions and behaviours that are crucial for understanding biology and biomedical research. Simply put, traditional structural biology has provided high-resolution images of biomolecules but is limited to static representations; integrative structural biology allows researchers to observe molecular movement and interactions in real-time within their biological environments. It also brings into light entire new classes of biomolecules—in particular, those that are dynamic and difficult to study as well as complexes of ever-increasing sizes. Thus, integrative structural biology not only expands the range of methods used to study molecular structure and function, but also substantially expands the scope of problems that can be addressed.
At this course, students will learn to understand, use, and interpret data from a multitude of different techniques including cryo-electron microscopy, nuclear magnetic resonance spectroscopy, X-ray crystallography, cryo-electron tomography, small-angle X-ray scattering, mass spectrometry, and single-molecule methods such as optical tweezers and Förster resonance energy transfer. Further, students will learn how to integrate data using advanced computational and machine learning techniques.
The course will include plenary lectures by esteemed scientists, poster sessions, panel discussions, journal club, group discussions, and a mentoring session led by Professor Emeritus Jane Clarke (University of Cambridge). These sessions will allow participants to receive practical feedback on their research projects, both from their peers and the participating senior scientists. In addition to the scientific activities, social dinners and an excursion around the island will also be organized.