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Biophysical methods for the real-time characterization of biomolecular interactions (Kinetics2025)
31 March – 4 April CEST
The MOSBRI Advanced Level School, ALS2, takes place in at Institut Pasteur, Paris. The real-time monitoring of binding kinetics provides a much more accurate representation of biological processes than end-point « equilibrium » measurements. Knowing how fast interaction partners associate and what is the time stability of biomolecular assemblies is crucial to understand the dynamics of living systems. The objective of the theoretical/practical “Kinetics2025” course is to illustrate the large diversity of biophysical methods that have been developed over the years for the determination of rates of association (kon) and dissociation (koff) in a variety of contexts, and to provide an invaluable opportunity to assess hands-on the strong points of a number of commercially available instruments.