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08:00
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Foyer | Registration opens
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09:00-09:45
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Plenary Hall | Plenary 6
Chair: Anthony Watts, UK
- Studying lipid/protein interactions: from self-assembled model membranes to native nanodiscs
J. Antoinette Killian, Utrecht University, Department of Chemistry, Membrane Biochemistry and Biophysics Group, NL |
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09:50-10:40
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Plenary Hall | S13 Biomolecular Simulation and Computational Biophysics
Chairs: Helmut Grubmüller, DE & Esteban Vöhringer-Martinez, CL
- The modelling of water dispersion and the properties of disordered protein states in simulation
Stefano Piana, D. E. Shaw Research, US
- Simulation of the function of biomolecular machines
Gerhard Hummer, Max Planck Institute of Biophysics, Department of Theoretical Biophysics, DE |
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Hall 1 | S14 Systems Biology and Multi-Cellular Systems
Chairs: Frank Jülicher, DE & Jacques Prost, FR
- Actomyosin force generation directs hydra regeneration
Kinneret Keren, Technion – Israel Institute of Technology, Physics Department, IL
- Mechanics of cell contacts during tissue morphogenesis
Pierre- François Lenne, Developmental Biology Institute of Marseille (IBDM), Physical approaches to cell dynamics and tissue morphogenesis, FR |
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Hall 2 | S15 Biologically Active Peptides
Chairs: Thomas Gutsmann, DE & Michel Lafleur, CA
- Peptide aggregation reduces the bioactivity of an HIV selective-inhibitor peptide
Cait E. MacPhee, University of Edinburgh, School of Physics and Life Sciences, UK
- Membrane destabilization by the HIV-1 gp41 MPER-TMD region: mechanism and blocking by antibodies
José Luis Nieva Escandón, University of the Basque Country, Biophysics Unit (CSIC-UPV/EHU), ES |
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10:40-11:10
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Exhibition | Coffee break
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11:10-12:20
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Plenary Hall | S13 continued Biomolecular Simulation and Computational Biophysics
- Computing the temperature dependence of chemical reactions inside and outside of living things
Johan Åqvist, Uppsala University, Department of Cell and Molecular Biology, SE
- Validation and development of force field parameters for drug and drug-like molecules
Katarzyna B. Koziara, The University of Queensland, School of Chemistry and Molecular Biosciences, AU
- Ubiquitin recruitment and transport by the proteasome unraveled by an orchestra of MD simulations
Till Rudack, University of Illinois, Department of Biophysics and Computational Biology, US
- Crucial role of non-specific interactions in amyloid nucleation
Andela Šarić, University of Cambridge, Department of Chemistry, UK |
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Hall 1 | S14 continued Systems Biology and Multi-Cellular Systems
- Quantitative morphology of epithelial folds
Primož Ziherl, University of Ljubljana, Faculty of Mathematics and Physics, SI
- Mechanical instabilities in epithelial monolayers: elastic waves in a viscous medium?
Jaume Casademunt, Universitat de Barcelona, Facultat de Física, ES
- On cancer risk and the number of stem cell divisions
Imre Derenyi, Eotvos University, Department of Biological Physics, MTA-ELTE “Lendulet” Biophysics Research Group, HU
- Absolute quantification of protein copy number in single cells using single molecule microarrays
Keith R. Willison, Imperial College London, Institute of Chemical Biology, Proxomics, UK |
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Hall 2 | S15 continued Biologically Active Peptides
- Structure and function of cell-penetrating peptides
Roland Brock, Radboud University Nijmegen, Medical Centre, Department of Biochemistry, NL
- Structure and dynamics of lantibiotics by molecular dynamics simulations: a fundamental approach towards antimicrobial activity
Alejandra de Miguel, Technische Universität Berlin, DE
- Cyclotides, stable drug scaffolds that enter cells after binding to PE-phospholipids
Sonia T. Henriques, The University of Queensland, Institute for Molecular Bioscience, AU
- Synthetic dendrimeric peptides with β-sheet structure and membranolytic activity
Ilaria Serra, University of Cagliari, Department of Chemical and Geological Sciences, IT |
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12:20-14:45
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Exhibition | Lunch break & poster session
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14:45-15:30
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Plenary Hall | Plenary 7
Chair: Ilpo Vattulainen, FI
- Synchronization of eukaryotic flagella
Raymond E. Goldstein, University of Cambridge, Centre for Mathematical Sciences, Department of Applied Mathematics and Theoretical Physics, UK |
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15:30-15:55
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Plenary Hall | New and Notable 3
Chair: Hans-Joachim Galla, DE
- Breaking the 3Å resolution barrier in single particle cryo-EM
Holger Stark, Max Planck Institute of Biophysical Chemistry, 3D Electron Cryo-Microscopy, DE |
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15:55-16:25
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Exhibition | Coffee break
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16:25-17:15
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Plenary Hall | S16 Membranes and Vesicles
Chairs: Kai Simons, DE & Manuel Prieto, PT
- Membranes and vesicles with bilayer asymmetry
Reinhard Lipowsky, Max Planck Institute of Colloids and Interfaces, DE
- Shaping and scission of membranes with BAR-domain proteins
Patricia Bassereau, Institut Curie, Membranes and Cellular Functions Group, FR |
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Hall 2 | S18 Protein Folding, Assembly and Stability
Chairs: André Matagne, BE
- Probing protein energy landscapes by high-pressure NMR
Jochen Balbach, Martin Luther University Halle-Wittenberg, Institute of Physics, Biophysics Group, DE
- Mechanism of assembly and shear force dependent adhesion of type 1 pili from uropathogenic E. coli
Rudolf Glockshuber, ETH Zürich, Institute of Molecular Biology and Biophysics, CH |
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16:25-17:25
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Hall 1 | S17 COST Symposium - Understanding Movement and Mechanism in Molecular Machines/CMST (COST Action CM1306) and Biophysics of GPCRs (GLISTEN - COST Action CM1207)
Chairs: Thomas Stockner, AT & Anthony Watts, UK
- Crystal structure of a class C GPCR – metabotropic Glutamate receptor 5 (mGluR5)
James Errey, Heptares Therapeutics, UK
- Unambiguous and quantitative identification of metals in proteins
Elspeth F. Garman, University of Oxford, Department of Biochemistry, Laboratory of Molecular Biophysics, UK
- Observing myoglobin proteinquake with an X-ray free-electron laser
Matteo Levantino, University of Palermo, Department of Physics and Chemistry, IT |
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17:15-17:25
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Foyer | Break
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17:25-18:35
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Plenary Hall | S16 continued Membranes and Vesicles
- Lipid bicontinuous cubic phases: effects of chain-branching and hydrostatic pressure
John M. Seddon, Imperial College London, Chemistry Department, UK
- Kinetics and thermodynamics of CPZ interaction with lipid bilayers: effect of charge and cholesterol
Patricia A. T. Martins, FCTUC, PT
- Receptor-mediated HDL-lipid uptake is regulated by elastic properties of the plasma membrane
Birgit Plochberger, Vienna University of Technology, AT
- Characterisation of membrane protein ZipA in SMALPs gives a complimentary SAXS and Cryo-EM 3D model
Sarah Lee, University of Birmingham, School of Biosciences, UK |
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Hall 2 | S18 continued Protein Folding, Assembly and Stability
- Protein folding and stability: From the test tube to the cell
Simon Ebbinghaus, Ruhr University Bochum, Department of Physical Chemistry II, DE
- Self-assembly kinetics of virus-like particles probed by time-resolved small-angle X-ray scattering
Didier Law-Hine, Université Paris-Sud, Laboratoire de Physique des Solides, FR
- Theoretical study of the dynamic heterogeneity in the protein folding/unfolding transitions
Toshifumi Mori, Institute for Molecular Science, JP
- Local motions within the Hsp90 molecular chaperone machinery observed by fluorescence quenching
Andrea Schulze, Julius-Maximilians-University Würzburg, DE |
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17:35-18:35
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Hall 1 | S17 continued COST Symposium - Understanding Movement and Mechanism in Molecular Machines/CMST (COST Action CM1306) and Biophysics of GPCRs (GLISTEN - COST Action CM1207)
- Dynamic GPCR dimerisation probed by ensemble and single-molecule FRET, DEER, and simulations
Patricia M. Dijkman, University of Oxford, Department of Biochemistry, Biomembrane Structure Unit, UK
- Understanding ligand binding and receptor selectivity through molecular simulations
Hugo Gutierrez de Teran, Uppsala University, Department of Cell and Molecular Biology, Computational and Systems Biology, SE
- Using smFRET to understand structure, function and dynamics of molecular machines
Dagmar Klostermeier, University of Muenster, Physical Chemistry, DE |
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19:30-23:30
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Terrace Level | Conference Dinner
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